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Based on the current level of evidence, other authors have also suggested the use of oral or topical glutathione as an adjunctive therapy for facial melanosis

These dedifferentiated adipocytes exhibit decreased expression of core adipogenic regulators but significantly upregulated expression of proinflammatory adipokines, such as IL-6 and IL-8, further reinforcing tumor-promoting metabolic dysregulation in the TME [128,129,130, 132]

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His contributions to these areas have provided him with a comprehensive understanding of the subject matter and the ability to tackle complex research challenges